After losing his wife seven years earlier, the eccentric Dr. John Dolittle, famed doctor and veterinarian of Queen Victoria’s England, hermits himself away behind the high walls of Dolittle Manor with only his menagerie of exotic animals for company. But when the young queen falls gravely ill, a reluctant Dolittle is forced to set sail on an epic adventure to a mythical island in search of a cure, regaining his wit and courage as he crosses old adversaries and discovers wondrous creatures.

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  • Robert Downey Jr.

    Dr. John Dolittle

  • Antonio Banderas

    King Rassouli

  • Michael Sheen

    Dr. Blair Müdfly

  • Jessie Buckley

    Queen Victoria

  • Jim Broadbent

    Lord Thomas Badgley

  • Harry Collett

    Tommy Stubbins

  • Emma Thompson

    Polynesia (voice)

  • Rami Malek

    Chee-Chee (voice)

  • John Cena

    Yoshi (voice)

  • Kumail Nanjiani

    Plimpton (voice)

  • Octavia Spencer

    Dab-Dab (voice)

  • Tom Holland

    Jip (voice)

  • Craig Robinson

    Kevin (voice)

  • Ralph Fiennes

    Barry (voice)

  • Selena Gomez

    Betsy (voice)

  • Marion Cotillard

    Tutu (voice)

  • Frances de la Tour

    Dragon (voice)

  • Ralph Ineson

    Arnall Stubbins

  • Tonya Cornelisse

    The Island Milkmaid

  • Chris Brazier

    Pirate Messenger

  • Zak Holland

    Palace Guard

  • Elliot Barnes-Worrell

    Captain Derrick

  • Daniel Hoffmann-Gill


  • Nasir Jama


  • Carmel Laniado

    Lady Rose

  • Stephen Samson

    Palace Guard

  • Clive Brunt

    Peeler #3

  • Joseph Balderrama


  • Joseph Segal

    Palace Guard

  • Tarik Mesfun


  • Shane Rawlings

    Palace Guard

  • David Cradduck


  • Michael Herne

    Rassouli Guard

  • Andrew G. Ogleby

    Queen's Valet

  • Joanna Page

    Bethan Stubbins

  • Sonny Ashbourne Serkis

    Arnall Stubbins Jr

  • Oliver Chris

    Sir Gareth

  • Clive Francis


  • Matt King


  • Jason Mantzoukas

    James the Dragonfly (voice)

  • John-Luke Roberts